Agent SDKs and orchestration frameworks

AG2AI (community) · Python

Community-run multi-agent framework that grew out of AutoGen, now built around agent networks, subagents and A2A.

Microsoft · Python, C#

Framework for building agents and multi-agent workflows in Python and .NET; the stated successor to both AutoGen and Semantic Kernel.

Google · Python, TypeScript, Go, Java, Kotlin

Open-source framework for building, evaluating and deploying agents and multi-agent systems, optimized for Gemini but model-agnostic.

Agno · Python

Python framework for building agents, teams and workflows, served through the AgentOS FastAPI runtime.

crewAI, Inc. · Python

Python framework for orchestrating role-based agent crews and event-driven Flows.

LangChain · Python, TypeScript

Low-level orchestration framework for building stateful, long-running agents as graphs with persistence and interrupts.

Mastra · TypeScript

TypeScript framework for building agents, workflows, memory and evals, with a local Studio for testing.

AWS · Python, TypeScript

Model-driven SDK for building agents in a few lines of code, with multi-agent swarm, graph and agents-as-tools patterns.

IBM Research (LF AI & Data project) · Python, TypeScript

Python and TypeScript framework for production multi-agent systems with rule-constrained RequirementAgent and workflows.

Pydantic · Python

Python agent framework built around typed, validated tools and outputs, with a separate graph library for complex control flow.

Cloudflare · TypeScript

TypeScript SDK for stateful agents on Cloudflare Workers and Durable Objects, with scheduling, workflows and MCP.

Vercel · TypeScript

TypeScript toolkit for LLM apps whose Agent abstractions add tool loops, subagents, tool approvals and durable workflow agents.

deepset · Python

Python framework for composable LLM pipelines and tool-using agents, often used for RAG.

LlamaIndex · Python, TypeScript

Data framework for LLM apps with event-driven Workflows and an AgentWorkflow class for multi-agent handoffs.

OpenAI · Python, TypeScript

Lightweight framework for building multi-agent workflows with agents, tools, handoffs, guardrails and tracing.

Inngest · TypeScript

TypeScript library for building agent networks with shared state and code- or LLM-based routers, deployable on Inngest.

CAMEL-AI.org · Python

Python multi-agent framework for role-playing agent societies and Workforce task delegation.

Anthropic · Python, TypeScript

Library that exposes the Claude Code agent loop, built-in tools and context management for building agents in Python and TypeScript.

Letta · TypeScript, Python

Platform for stateful agents with persistent memory (formerly MemGPT), with an agent harness, server and SDK.

Hugging Face · Python

Minimal Python library for agents that write and execute Python code as their actions.

Temporal Technologies · Go, Java, Python, TypeScript, .NET, PHP, Ruby

Durable execution platform whose Workflows and Activities are used to make agent loops reliable, with an AI cookbook of agent patterns.

Stanford NLP · Python

Framework for programming language models with declarative modules and optimizers, including ReAct-style tool-using agents.